Skip to main content

Peyronie’s disease

What is Peyronie’s disease?

Why does Peyronie's disease appear?

Peyronie’s disease is the result of repeated injury to the penis. For example, the penis can be damaged during sexual intercourse, athletic activity, or as a result of an accident.

When these types of injuries heal, they leave a fibrous tissue in the shaft of the penis that makes it impossible for it to stretch thoroughly, giving rise to curvature.

Signs and symptoms

  • Palpation of a complex, fibrous plaque under the skin
  • Significant curvature of the penis. This can be up, down, or to the sides
  • Erection problems/li>
  • Penis shortening
  • Pain during erection


Peyronie’s disease does not go away on its own, and in most cases, it usually worsens without proper treatment.

The treatment consists of eliminating or making the fibrous plaque more elastic so that the curvature decreases or disappears and the patient can return to an everyday sexual life.

The most effective minimally invasive procedures are Shockwave therapy and collagenase enzyme infiltration.

Shockwave Therapy

This therapy consists of low-intensity extracorporeal shock waves applied directly to the area where the fibrotic plaque is located, increasing the area’s vascularity and stimulating the plaque’s degradation, causing curvature.

The best results are obtained by giving two weekly sessions for three weeks, with an interval of 3 weeks without treatment, and repeating another two weekly sessions for three weeks.

Features of Shockwave therapy

Outpatient Procedure.

It is done in 30 minutes.

Does not cause pain.

Immediate recovery.

Does not cause any pain.

All men, without exception, are candidates for the procedure.

Clostridium histolyticum collagenase injection

Clostridium histolyticum collagenase is an enzyme which breaks down the collagen deposits that form in the scar tissue of the penis, softening and reducing the curvature of the penis.

Clostridium histolyticum collagenase injection features

It is performed on an outpatient basis.

No pain or scar

It is placed once a month until the patient recovers his natural shape or can have non-painful sexual activity

Immediate recovery to work

In expert hands, there are no risks in its placement

Surgical procedures to eliminate Peyronie's disease

These are reserved exclusively when minimally invasive therapies fail to allow the patient to correct the curvature and have a whole sexual life sufficiently.

Plication of the tunica albuginea or modified Nesbit plastic

It is the most commonly performed surgical treatment to correct curvature.

This technique consists of placing reins or sutures on the opposite side of the curvature, exerting traction, and correcting the curvature.

This technique has the side effect of shortening the penis, but nowadays, it is usually performed in conjunction with a section of the penile suspensory ligament, which counteracts the shortening.

Erectile function is not affected by this technique.

Plaque Excision and Placement of Grafts or Patches

This surgical technique consists of removing the fibrotic plaque responsible for the curvature and replacing it with an elastic biological patch that counteracts it. It is indicated in severe cases with curvatures more significant than 70° and excellent
erectile function.

Unlike the Nesbit plastic, it does not generate shortening. Still, it does increase the risk of venous leak, which translates into erectile dysfunction.

Testimonials from my patients


More than 700 opinions from our patients support us.

Me sentí muy cómodo con el Dr. Ayala Lizarraga, me explicó detalladamente mi padecimiento e hizo que me quedara más tranquilo después de la consulta, le agradezco mucho por su tiempo y su atención.

Fernando Ruiz

Tuve una experiencia 10/10. Pienso que tiene un criterio muy acertado el Dr. da confianza y se toma el tiempo para explicar cualquier duda. Muy recomendable 100%.

Antonio de Jesús Castro

Excelente recuperación después de mi operación. El doctor es muy amable y explica bien todo el proceso. Excelente atención, lo recomiendo 100%.

Erik Fragoso

Service was excellent, my visit went smoothly. Communication leading up to my visit was great . All my questions and concerns were answered.

K Williams

Schedule an appointment on Doctoralia

Jesus Uriel Ayala Lizarraga -
Abrir chat
Agenda por WhatsApp